QS Study

Milieu Interior – a term introduced more than 100 years ago by the French physiologist Claude Bernard.

Definition: Extracellular fluid is called the milieu interior or internal environment. Its physiological capacity to ensure defensive constancy for the tissues and organs of the multicellular organism.

Mechanism: In the ECF, are the ions and nutrients needed by the cells for maintenance of cellular life. So all cells live essentially in the same environment, the ECF. So, it is called internal environment.

It is the bodily fluids regarded as an internal environment in which the cells of the body are nourished and maintained in a state of equilibrium

Proper conc, of O2 glucose, different ions, amino acids, salts, substances and other constituents are available in that internal environment which is necessary for living, growing and performing the special functions of the cells. All fundamental processes essential for the continuance and life of the tissue elements depend on the constancy and stability of this environment.