QS Study

Pregnancy Tests are a medical test which women have to find out if they have become pregnant. A pregnancy test measures a hormone in the body called human chorionic gonadotropin (HCG). HCG is a hormone formed during pregnancy. It appears in the blood and urine of pregnant women as early as 10 days after conception.

The pregnancy tests are –

(A) Laboratory tests for pregnancy:

(i) Modern method: Immunologic test:

  • Direct agglutination test
  • Indirect agglutination test.

(ii) Biological method:

  • Friedman test,
  • Ascheim – zondek test,
  • Kupperman test,
  • Hoggben test,
  • Galli manini test,

(iii) Radioimmunoassay,

(iv) Enzyme Immunoassay.

(B) Special test:

  • Ultrasonography
  • X-ray (after 32 weeks)
  • Fetal heart sound.

 

The principle of pregnancy test:

Mainly based on antigen and antibody reaction. HCG in urine is the antigen and antibody developed against HCG after administration of HCG in rabbits. This anti-HCG is taken from those rabbits and is used to detect the presence of HCG in pregnant women’s urine. Inhibition agglutination means (+) pregnancy test.

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