QS Study

Oxygen Toxicity

Oxygen is necessary to life in an aerobic organism. But it may be toxic. Toxicity seems to be due to the production of superoxide anion (O2) which is free radical, and H2O2. It is a condition resulting from the harmful effects of breathing molecular oxygen at increased partial pressures. Oxygen deprivation dangerous and patients who are in danger for this must be placed on high attention oxygen therapy in spite of the chance of oxygen toxicity. The solution to avert the toxicity is to use the lowest level oxygen probable that is still helpful to the patient.

Signs and symptoms – Oxygen may be necessary to life but it must be received in a definite awareness to attain the desired biological benefit. If this gas is inhaled in concentrated form, it can be toxic to human and may lead to several symptoms.

  • Substernal distress
  • Nasal congestion
  • Sore threat coughing
  • Muscle twitching
  • Ringing in the ears
  • Dizziness of the eye
  • Convulsion
  • Coma.

There are two widely recognized types of oxygen toxicity, which is also known as oxygen poisoning or oxygen intoxication. Each type has its own distinctive set of symptoms. Named for the systems of the body that they affect, these are pulmonary oxygen toxicity and central nervous system (CNS) oxygen toxicity.


  • Broncho pulmonary dysplasia
  • Retroventral fibroplasia etc.

Human tolerance to oxygen toxicity must be defined over a range of useful pressures to derive maximal benefit from therapeutic applications of hyperoxia while avoiding concurrent adverse effects./ul