QS Study

The liver is the largest solid organ and the largest gland in the human body. It is located below the diaphragm in the right upper quadrant of the abdominal cavity. It is a metabolically active organ accountable for many vital life functions. It carries out over 500 essential tasks. Many dissimilar sickness procedures can happen in the liver, including infections such as hepatitis, cirrhosis, cancers, and damage by medications or toxins.

Functions of Liver –

Fig: Functions of Liver

(1) Formation and secretion of Bile,

(2) Bile production: Bile helps the small intestine break down and absorb fats, cholesterol, and some vitamins.

(3) Nutrient and vitamin metabolism: Liver is the main site for metabolism of CHO, protein and lipids. It is also the site for fat and water-soluble vitamin and alcohol metabolism.

(4) Plasma protein synthesis: Liver synthesizes albumin, dotting factors, steroid and hormone binding proteins. S, α-FP, Angiotensinogen etc.

(5) Storage function: CHO, protein, and fat are stored in liver in the form of glycogen. Fat-soluble Vit (A, D, E, K) and iron are menus stored in it.

(6) Detoxification function: Liver is the main site for detoxification of NH3, drugs, steroid, hormones toxins etc.

(7) Excretory function: Liver excretes heavy metals (Bi, As, Pb) Cholesterol, bile pigment etc.

(8) Haemopoietic function: Liver is the main organ for haemopoiesis in early life.

(9) Immunity: Kupffer cells of liver acts as macrophage.