QS Study

Gastric Juice is the mixture of secretions from all the glands present in the stomach. The production of gastric juices is limited while a person is asleep, but production resumes upon awakening. It is most helpful in digestion of food. It consists of Enzymes present in the stomach. It helps in absorbing the food in the body very easily. They are secreted by glands lining the stomach and function to break down food in the stomach and kill bacteria.

Basic Functions of Gastric Juice –

  • Presence of HCL makes the juice antiseptic,killing almost all the germs entering with food
  • Pepsinogens are converted to pepsins with the help of HCL and helps in protein digestion
  • Iron absorption
  • Gastric lipase helps in lipid digestion.

Fig: Gastric Juice

(1) Digestive functions –

It helps in digestion by enzymes –

Protein → by pepsinogen

Fat → by Gastric lipase

Milk → by Renin.

(2) Excretory function – Heavy metals, toxins, certain alkaloids are excreted by Gastric Juice.

(3) Haemopoietic function –

The intrinsic factor of the castle of gastric juice helps in Vit B12 absorption from gut which is essential for RBC maturation.

(4) Function of HCl/ Gastric Juice

  • Gastric HCl converts inactive pepsinogen into active pepsin.
  • Gastric HCl acts as an antiseptic agent against bacteria.
  • It hydrolyzes all food stuffs.
  • It keeps an iron in the ferrous state for absorption.
  • Pepsinogen digests protein up to the stage of peptone due to the presence of gastric HCl.
  • It provides a suitable environment for the action of an engine.
  • It maintains a proper environment for gastric emptying.
  • It converts collagen protein into gelatin.
  • It hydrolyzes cane sugar to glucose and fructose.
  • It helps in the dissolution of the protoplasmic covering of the fat globules.

(5) Lubricating imitator – The musin of gastric juice lubricates irritant food staffs.

(6) Protection of stomach – The mucin protects the gastric mucosa from HCl. Thus it is not self-digested.

(7) Acid-base regulation – It is responsible for the alkaline tide of blood, during secretion of HCl.