QS Study

Endocrine functions of Kidney

Functions of the kidney – The primary function of the kidneys is to sustain the accurate stability of water and minerals in the body. The kidneys cooperate a supplementary vital role in helping to control activities of the endocrine system, secreting two hormones and an enzyme that participate vital roles in amendable red blood cells, healthy bones, and blood pressure.

Formation of urine: It maintains the internal environment by maintaining –

a) Water balance,

b) Electrolyte balance,

c) Acid-base balance

Excretory Function:

  • It excretes metabolic waste products like urea, uric acid, creatinine etc. and toxic and foreign substances like a drug, bilirubin etc.
  • It conservatives nutrition e.g. glucose, amino acid, vitamins, etc.

Fig: Endocrine functions of Kidney

Endocrine function: Kidney produces

(i) Erythropoietin: Stimulates erythropoiesis. It is a peptide hormone which regulates erythropoiesis.

(ii) Renin – It regulates blood pressure (B. P.)

(iii) 1, 25 – dihydroxycholecalciferol. It is active Vit-D3 and helps in dietary Ca2+ and PO43- absorption.

(iv) Prostaglandins- It acts as a local mediator and helps in vasodilation.

(v) Kinins.

Other functions

(i) It regulates arterial pressure by excreting variable amounts of Na+ and H2O and vasoactive substances like Renin.

(ii) It synthesizes glucose from non-CHO source by a process called gluconeogenesis.

(iii) It helps in maintaining blood glucose level during prolonged fasting.

(iv) It is the main organ for drug excretion.size-full wp-image-30440 aligncenter