QS Study

Difference in Filtration of Glomerular Capillary and other Capillary

The quantity of glomerular filtrate formed per minute in all the functioning nephrons of both kidneys is called glomerular filtration rate (GFR). It is a test used to check how well the kidneys are working. Glomerular capillary is more permeable than other capillaries because glomerular capillary consists of 3 layers.

These are –

  1. Capillary endothelium.
  2. Basement membrane.
  3. Podocycle or Bowman’s capsule.

Fig: Filtration of Glomerular Capillary

The blood plasma is filtered through the capillaries of the glomerulus into the capsule. The Bowman’s capsule empties the filtrate into the proximal tubule that is also part of the duct system of the nephron. A glomerulus receives its blood supply from an afferent arteriole of the renal circulation.

Glomerular capillary (GC) is highly fenestrated capillary i.e., the gap between the adjacent endothelium is very high (70-90 nm). In other spaces, the distance is (10-20 nm). So the peculiarities or arrangement of the endothelium of glommular membrane make it more/highly permeable than other capillaries.

Filtration slits in pseudopodia have a diameter of 25 nm.http://www.qsstudy.com/wp-content/uploads/2018/05/Filtration-of-Glomerular-Capillary-1-1.jpg