QS Study

Definition: Acclimatization is the adaptation of body tissue in response to long-term exposure to hypoxia at high altitude. It is the procedure in which a person organism adjusts to a transform in its environment (such as a change in altitude, warmth, moisture, photoperiod, or pH), allowing it to sustain performance across a range of environmental conditions.

Responses for acclimatization at high altitude

The several impulsive changes that evoke rapid and short-term responses via the nervous and hormonal systems are not examples of acclimatization. An individual organism can regulate its internal processes quickly to maintain itself within the standard variety of environmental changes that it encounters hourly or daily.

  • ↑ Pulmonary ventilation (up to 1.65 times acutely and 5 fold)
  • Red Blood Cell. (polycythemia) (PCV 60 ml/ ml)
  • ↑ Hb conc. (50%)
  • ↑ Circulatory blood volume
  • ↑ Diffusion capacity of the lungs (3 fold)
  • ↑ Tissue vascularity
  • ↑ Ability of the cells to utilize oxygen despite the low PO2.

In the Andes and Himalayas, there are permanent human habitats at an elevation above 5500 m. (18000 ft). The natives who live in these villages are barrel-chested and markedly polycythemic.