QS Study

Role of different Hormones on Breast at a different stage

Hormone balance is key to breast health, as well as overall health. Both established and evolving breast cancer research points to the roles of estrogen, progesterone, testosterone, DHEA, cortisol, and thyroid and Vitamin D as key players in breast cancer prevention.

(1) At Puberty

  • Estrogen – Development of stroma and ductile system. Determining symptoms of estrogen dominance is a smart move since an imbalance of high estrogen too low progesterone.
  • Progesterone – Development of lobules and alveoli.
  • Prolactin – Causes ductile proliferation and growth.
  • Insulin and Gil – Causes ductile proliferation and growth in response to other hormones

(2) During pregnancy:

Prolactin –

  • Causes final lobuloalveolar development,
  • Some milk accretion takes place.

Estrogen and progesterone: They play leading roles in orchestrating appropriate growth and function of breast tissue. High levels of these hormones are linked with pregnancy and emerge to be accountable for the reducing risk for breast cancer among women following a full-term pregnancy.

  • Inhibition of the actual secretion of milk.
  • Final tubuloalveolar development along with prolactin.

Placental hormones: Human chorionic somatomammotropin (HCS), estrogen, and progesterone – the help in the development of the breast.

Glucocorticoid, insulin, and GH: Take part in final tubuloalveolar development.

(3) After delivery: Decreased estrogen and progesterone: allows lactogenic effects of prolactin.