Regulation of Pancreatic Juice Secretion - QS Study
QS Study

Pancreatic Juice is a juice that contains multiple types of enzymes for all type of food digestion. The pancreas makes pancreatic juices and hormones. It contains enzymes that help digest food in the small intestine. It is the product of two distinct types of secretory processes: enzyme secretion and electrolyte secretion. The release of these hormones into the blood is stimulated by the entry of the acidic chyme into the duodenum.

Pancreatic juice secretion is regulated by –

(i) Nervous regulation

(ii) Hormonal regulation

Nervous regulation: It acts through vagus and cholinergic nerve fiber. During gastric secretion occurs, automatically parasympathetic impulses are transmitted to the pancreas by vagus nerve resulting in acetylcholine secretion. Acetylcholine acts on the pancreas and releases pancreatic juice which is rich in enzyme and poor in HCO3.

(ii) Hormonal regulation:

(a) Cholecystokinin: It is secreted by the duodenal and upper jejunal mucosa when fatty food enters the small intenstine.

(b) Secretin: It is secreted by duodenal and jejunal mucosa when highly acid food enters the small intestine.