QS Study

Postprandial Alkaline Tide

Alkaline Tide is a condition of increased alkalinity of the body fluids and urine during digestion associated with the loss of acid by secretion of gastric juice. After meal gastric acid secretion is elevated. As a result, gastric acid secretion is elevated. Thus blood pH is elevated. This results in compensatory loss of HCO3 in urine. Thus, after a meal, urine becomes alkaline. This is called postprandial alkaline tide.

Fig: Postprandial Alkaline Tide

The postprandial alkaline tide occurs as a result of meal ingestion and the subsequent excretion and loss of gastric acids. It is attributed to HCO3 discharge resulting to H+ secretion. Any procedure which reduces acid secretion is expected to affect the postprandial urinary pH. The concept of an alkaline tide which compensates for gastric acid secretion suggests the possibility of indirect measurement of gastric acid secretion.

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