Pancreatic Juice: Composition and Daily Secretion - QS Study
QS Study

Pancreatic juice

It is a juice that contains multiple types of enzymes for all type of food digestion. The pancreas makes pancreatic juices and hormones. It contains enzymes that help digest food in the small intestine. It is the product of two distinct types of secretory processes: enzyme secretion and electrolyte secretion. The release of these hormones into the blood is stimulated by the entry of the acidic chyme into the duodenum.

Daily secretion: 800-1500 ml/ day

  • Avg : 1500 ml /day
  • pH: 8.0 – 8.3
  • Reaction: Strongly alkaline

Fig: Pancreatic juice


  • Water: 98.5%
  • Solid: 1.5%


Enzymes: It contains enzymes for digestion of all three major types of food (CHO, Protein, and Fat)

(i) Proteolytic: Trypsin (trypsinogen), chymotrypsin (Chymotrypsinogen), Carbonylpolypeptidase (procarbonypoly peptidase), RNAase, DNAase

(ii) CHO splitting enzyme: Pancreatic alpha-amylase

(iii) Fat splitting enzyme: pancreatic lipase, cholesterol esterase, phospholipase.


(i) Cations: Na+, K+, Ca++, Mg++ etc.

(ii) Anions: Large amount of HCO3, Cl, SO4-2, HPO4-2 etc.