QS Study

Individual Functions of Plasma Protein

The proteins, which are distinct from structural protein, remains in plasma are called plasma proteins. The proteins present in the plasma of human blood are a mixture of simple proteins, glycoproteins, lipoproteins and other conjugated proteins are called “Plasma Proteins“. It acts as a source of protein for the tissues, whenever the need arises.

Albumin – It is synthesized in liver and consists of a single polypeptide chain of 610 amino acids having a molecular weight of 69,000.

  • Maintains 75% of total colloidal osmotic pr.
  • Maintains viscosity of blood.
  • Acts as a buffer and maintain acid-base balance.
  • It acts as a carrier of protein and transport of hormone, amino acid, lipids, bilirubin, vitamins, drugs etc.
  • It acts as a protein reservoir.

Globulin – The average normal serum globulin (total) concentration is 2.5 gm / 100 ml (Howe method) or 3.53 gm/100 ml by electrophoresis.

  • It regulates 20% of total colloidal osmotic pr. of blood.
  • It helps to maintain the viscosity of blood.
  • L1- globulin transports lipid and steroids.
  • L2- globulin transports Cu as ceruloplasmin.
  • α- globulin transports Fe as transferring.
  • γ- globulin acts as an antibody.

Fibrinogen- Fibrinogen plays an important role in the clothing of blood where it is converted to fibrin by thrombin.

  • Essectioal for coagulation of blood.
  • Maintain viscosity of blood.

Prothrombin: Take part in coagulation of Blood.

Others functions of plasma protein: It helps in the carnage of carbon dioxide, by forming carboamino protein. It forms triphone which helps in nutrition, growth, and repairs of tissue.

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