QS Study

End-diastolic Volume (E.D.V)

The volume of blood remains in the ventricle at the end of ventricular diastole. It is the capacity or the amount of blood in the ventricle instantly before a cardiac contraction begins; a measurement of cardiac filling between beats, related to diastolic function. It is the volume of blood in the right and/or left ventricle at end load or filling in (diastole) or the amount of blood in the ventricles just before systole.

It is about 110 – 120.

Factors affecting the EDV

This is the amount of blood the veins return to the heart before contraction. Because there is no true test for preload, doctors may calculate left-side end-diastolic volume as a way to estimate preload.

  • Filling time: ↑ HR → ↓ Filling time → ↓ EDV
  • Effective filling pressure: ↓ CVP → ↑ Filling pressure → ↑EDV
  • Distensibility of ventricle: ↓ VD → ↓ EDV
  • Arterial contraction: ↑ A. C → ↑ EDV
  • Venous return: ↑ VR → ↑ EDV
  • Ejection fraction: ↑ EF → ↑ EDV

The fraction of blood that is ejected in systol is called EF. For an average-sized man, the end-diastolic volume is 120 milliliters of blood and the end-systolic volume is 50 milliliters of blood. This means the average stroke volume for a healthy male is usually about 70 milliliters of blood per beat.

Related Study: