QS Study

Hyperparathyroidism is a surplus of parathyroid hormone in the bloodstream due to overactivity of one or more of the body’s four parathyroid glands. These glands are about the size of a grain of rice and are located in your neck. The most familiar symptoms of hyperparathyroidism are chronic fatigue, body aches, complexity sleeping, bone pain, memory loss, poor awareness, and headaches.

Effect of Hyperparathyroidism

  1. Hypercalcemia and hypophosphatemia,
  2. ↑ Osteoclastic activity
  3. Osteoblastic activity – bone decreases,
  4. ↑ Renal excretion of PO43-,
  5. ↓ Excitability of muscle and nerve fiber → depressed CNS and peripheral nervous system → Muscle weakness.
  6. Constipation, abdominal pain, peptic ulcer, lack of appetite.
  7. Depressed relaxation of the heart during diastole and Metastatic calcification,
  8. Excessive mobilization of Ca++ and PO43- from bone leads to thinking of bone.
  9. ↑ Ca++ → kidney stones.