Differences between racemic mixture and meso compound
- The equimolar mixture of two enantiomers is called racemic mixture e.g (+) and (-) lactic acid forms (±) – lactic acid as racemic mixture.
- Racemic mixture is optically inactive due to external compensation.
- It can be separated into two enantiomers which are optically active.
- Racemic mixture may be formed from one or more than two asymmetric centres.
- A meso compound has at least two identical asymmetric centers with a plane of symmetry e.g. meso tartaric acid.
- Meso compound is optically inactive due to internal compensation.
- Meso compound is a single compound which cannot be separated into optically active compound by resolution process.
- Meso compounds should have at least two identical chiral centres.