Stages of Mitosis - QS Study
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Mitosis is a continuous process. The process is completed by a complex method. According to the sequence and stages, this continuous process is divided into five stages. The stages are:

(1) Prophase,

(2) Pro-Metaphase,

(3) Metaphase,

(4) Anaphase and

(5) Telophase.

Prophase: At this stage, the nucleus swells up. Chromosomes begin to be de- hydrated. As a result, the chromosomes gradually become shorter and thicker.

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Then they are visible under microscopes. At the end of this stage nucleolus and nuclear membrane become disappear.

Pro-Metaphase: At the beginning of this stage. the fibrous protein converse to form a bi-polar spindle apparatus. Each chromosome is then become attached to a fibre of the spindle apparatus by its centromere. Each fibre of the spindle apparatus is called spindle fibre. The fibre to which the chromosomes are attached is called fraction fibre. As they are attached with the chromosomes so they also called chromosomal fibre. In animal cell aster rays are radiated from centrioles present at two poles.

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Metaphase: Chromosomes are arranged at the equatorial plane of the spindle. The centromere of each chromosome remains at the equatorial plane and the two arms are placed towards two poles. At this stage, the chromosomes become maximum thick and short. Two chromatids of a chromosome become maximum thick and short. Two chromatids of a chromosome become clearly visible and the centromere is divided in to two parts.

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Anaphase: Two separate chromatids of a chromosome move towards the opposite pole of the spindle apparatus. Centromere goes ahead at the movement of the chromatids towards the pole and the arms follow them. when the daughter chromosomes reaches near the poles the anaphase stage ends.

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Telophase: Daughter chromosomes take position at two opposite poles. Chromosomes gradually take water and become elongated, thin and long. Nuclear membrane develops encircling the chromosomes. Nucleolus reappears at the secondary constriction of the Sat chromosome. Spindle apparatus disappears. At the end of this stage, gradually a cell wall develops at the equatorial region of the cell.

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